AVRI Panel Multiplex
A test for detecting and differentiating 16 most common pathogens of AVRI by reverse transcription and real-time PCR.
Acute viral respiratory infections
Acute viral respiratory infections (AVRI) is a broad spectrum of diseases of viral etiology, characterized by damage to the upper and lower respiratory tract. AVRI can be caused by RNA-containing viruses (pneumoviruses, paramyxoviruses, coronaviruses, picornaviruses, orthomyxoviruses) and DNA-containing viruses (adenoviruses and parvoviruses), which have tropism for the mesenteric epithelium of the respiratory tract. Differential diagnosis of acute respiratory infections, including influenza and COVID-19, is necessary to gauge the severity of the disease, predict complications and prevent hospital-acquired infections.
The incubation period for acute viral respiratory infections ranges from 1 to 14 days. The clinical picture of the disease depends on the type of pathogen, the viral load, the age of the patient and the presence of comorbidities. Acute viral respiratory infections can manifest as sore throat, sneezing, rhinorrhea, general weakness, fever, headache, cough, muscle and joint pain.
AVRI Panel Multiplex detects the nucleic acids (RNA or DNA) of 16 most common AVRI pathogens, including:- respiratory syncytial virus (RSV);
- parainfluenza virus types 1-4;
- rhinovirus;
- adenovirus;
- metapneumovirus;
- coronaviruses HKU1, 229E, OC43, NL63, SARS-CoV-2;
- bocavirus;
- influenza A viruses;
- influenza B virus.
Complications of AVRI
Preschool children, the elderly and patients with severe chronic diseases and immunodeficiencies are most susceptible to infection. AVRI can lead to serious pregnancy complications due to the high susceptibility of pregnant women to viral diseases. Acute viral respiratory infections can be mixed with bacterial infections, leading to complications such as sinusitis, otitis media, bronchitis, pneumonia, exacerbation of COPD and bronchial asthma. Specific complications of AVRI are acute respiratory failure, adult respiratory distress syndrome, infectious toxic shock syndrome, acute heart failure and meningism.
Indications for testing
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Irritated or sore throat -
Fever -
Body aches and muscle pain
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Cough -
Nasal congestion, runny nose -
Close contact with an AVRI patient -
Stay in hotbeds of infection -
Differential diagnosis
AVRI Panel Multiplex
The AVRI Panel Multiplex REAL-TIME PCR Detection Kit is an in vitro Nucleic Acid Test (NAT) – pathogen-detection-based product. The AVRI Panel Multiplex REAL-TIME PCR Detection Kit is designed to detection of the most common causative agents of acute viral respiratory infections by Real-Time PCR method.
Samples: nasopharyngeal swabs, oropharyngeal swabs, bronchoalveolar lavage, endotracheal aspirate, nasopharyngeal aspirate, phlegm.
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Please note that the specialists of the DNA Technology company provide consultations exclusively to medical specialists on the application and research features. Requests related to the appointment, delivery, or interpretation of tests are not considered. For relevant information, we recommend contacting the laboratory directly.