PCR testing in oncology practice

Advantages of real-time PCR

• High sensitivity and specificity: PCR is able to detect even low concentrations of oncogenic mutations in a sample.
• Quick results: PCR test results can be obtained within a few hours.
• Minimum sample quantity: PCR diagnostics require a small amount of biomaterial, which is especially important when access to samples is limited.

Studying mutations in the EGFR gene

The EGFR signaling pathway is involved in regulating cell growth, division, survival and death. The presence of activating mutations in the EGFR gene leads to proliferation of tumor cells and increased tumor invasiveness. Determining the mutation spectrum is important for prescribing targeted therapy with tyrosine kinase inhibitors to patients with non-small-cell lung cancer.
PCR diagnostics with "Genetics EGFR" reagent kit allows to quickly and accurately detect the most common mutations in the EGFR gene using formalin-fixed paraffin-embedded tumor samples of patients with non-small-cell lung cancer.

Detecting mutations in BRCA 1 and 2 genes

Mutations in the BRCA1 and BRCA2 genes are associated with a risk of hereditary forms of breast and ovarian cancer. The “BRCA Mutations” kit (ОнкоГенетика BRCA) enables identification of the most common mutations in the BRCA 1 and BRCA 2 genes. It is important to note that the test detects an increased risk of malignancies and aids in selecting a therapeutic approach based on knowledge about the mutation status. It is, however, impossible to reach a definitive diagnosis of neoplasm presence based solely on the test result!

PCR-based diagnostics of human papillomavirus (HPV)

Human papillomavirus is the main etiological factor in the development of cervical cancer. An effective method of preveting cervical cancer is HPV screening and treatment of precancerous conditions. PCR-based HPV diagnostics enable the quantification of specific virus types, which is widely used for preventing HPV-associated cancers.

Our research

• Genetics

  PCR diagnostics opens up wide possibilities for detecting genetic mutations that play a crucial role in the development of various diseases. This allows not only to diagnose and prevent the development of diseases at an early stage, but also to provide an individual approach to treatment and the choice of drug therapy.
  
  

  • BRCA Mutations
  • EGFR
• Papillomavirus infection

  Currently, over 100 types of human papillomavirus (HPV) have been identified, of which about 30 are capable of infecting the epithelium of the urogenital tract.
  
  

  • HPV Screen
  • HPV QUANT
  • HPV 16,18

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Please note that the specialists of the DNA Technology company provide consultations exclusively to medical specialists on the application and research features. Requests related to the appointment, delivery, or interpretation of tests are not considered. For relevant information, we recommend contacting the laboratory directly.

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