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PCR-based laboratory diagnostics for urologists and andrologists

Diagnosing male urogenital infections, analyzing UGT microflora, identifying possible causes of reproductive dysfunction.

Laboratory diagnostics for urologists and andrologists: PCR-based analysis of microbiota and urogenital tract infections in men

Modern urology and andrology require the use of laboratory diagnostic methods to accurately and timely determine the etiology of various conditions. PCR diagnostics holds an important place in andrologist’s practice, allowing the doctor to assess the microbiota balance in the urogenital tract, as well as to detect sexually transmitted diseases (STDs).
Real-time PCR method is not only an accessible tool for accurate pathogen detection and analysis of UGT microbiota, but also for genetic testing.

Male urogenital tract microbiota

Male UGT microbiota plays an important role in maintaining reproductive health. An imbalance of the microbiota can cause a variety of health issues, including prostatitis, urethritis and other urogenital diseases.
With the help of PCR testing, the doctor can determine the composition of UGT microbiota, identify any possible abnormalities and prescribe the necessary treatment to rectify them. This diagnostic method has high clinical significance, as it detects even those types of microorganisms that are difficult or impossible to detect using other methods.

UGT infections in men

Male urogenital tract infections can lead to severe complications, including inflammatory processes in the prostate and urethra, epididymitis and infertility.
Among the most common pathogens detectable by PCR are chlamydia, mycoplasmas, ureaplasmas and gonococci. High sensitivity of PCR diagnostics makes it possible to identify these pathogens in a timely manner and prescribe etiotropic treatment.

Genetic causes of infertility

Genetic factors are responsible for up to 50% of severe spermatogenesis disorders. Deletions in the azoospermia factor (AZF) locus account for roughly 15% of such cases. Molecular genetic methods are the recommended tool for detecting microdeletions in this locus. The use of real-time PCR to identify microdeletions in the AZF locus makes it possible to diagnose male factor infertility during pregnancy planning and decide on the use of assisted reproductive technologies.

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Please note that the specialists of the DNA Technology company provide consultations exclusively to medical specialists on the application and research features. Requests related to the appointment, delivery, or interpretation of tests are not considered. For relevant information, we recommend contacting the laboratory directly.

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