PCR tests for diagnostics and disease prevention in children

Analyzing gut microbiota of children

Analyzing children’s intestinal microbiota by PCR allows not only to assess the presence of pathogenic microorganisms, but also to determine the state of gut microbiota based on the ratio between normal and opportunistic microbiota. The «Enteroflor® Kids» reagent kit includes taxa that make up at least 99.9% of the representatives of children’s intestinal microbiota.

Molecular genetic diagnosis of viral infections

PCR allows to accurately identify Epstein-Barr virus (EBV), smallpox virus (VARV), cytomegalovirus, hepatitis B and C viruses, and herpes viruses. Early identification of these infections is crucial for initiating timely treatment and preventing complications.

Diagnosing acute respiratory viral infections

PCR aids prompt identification of viral agents causing acute respiratory infections, including various types of influenza, SARS-CoV-2 and respiratory syncytial virus. This is especially important during the epidemic season for early diagnosis and prevention of virus spread.

Diagnosing nosocomial infections and antibiotic resistance

Nosocomial infections pose a major threat to children in hospital settings. PCR allows to identify causative agents of nosocomial infections in a few hours, as well as provides information about their resistance to antibiotics to help prescribe effective treatment.

PCR screening for newborns

Neonatal screening helps identify the most common diseases that threaten the life and health of babies. Neonatal screening allows doctors to diagnose the disease at the preclinical stage, start treatment in a timely manner and avoid major complications. Molecular genetic methods are the diagnostic standard for spinal muscular atrophy (SMA) and primary immunodeficiency in newborns, and it can also be used to confirm monogenic diseases.

Advantages of PCR diagnostics in pediatrics:

• High sensitivity and specificity: PCR shows high diagnostic accuracy, minimizing the likelihood of false negative or false positive results.
• Quick result: results are usually available within a few hours, which is critical for providing timely medical care.
• Multiplex testing: allows multiple pathogens or genetic markers to be detected simultaneously in one test tube, which saves time and reduces the cost of testing.

Our research

• Identification of antibiotic resistance genes

  The GLA BAKRESIST study is designed to identify genes of resistance to glycopeptide and beta-lactam antibiotics in DNA preparations.
  
  

  • BacResista GLA
• Fungal infections

  A real-time PCR study makes it possible to identify the causative agent of infection with precision to the type in the shortest possible time for the correct selection of an antimycotic drug.
  
  

  • MycosoScreen
• Herpesvirus infections

  Fast and accurate PCR diagnostics of the main herpes viruses makes it possible to detect infection at an earlier stage of the disease than the serological examination method.
  
  

  • Herpes multiplex HSV1/HSV2/CMV
  • CMV-GEN
  • Epstein-Barr virus
  • HHV6
  • HHV8
• Microbiota research

  Comprehensive study of the composition of the microbiota of the large intestine in children from 0 to 14 years old. It allows us to accurately determine the quantitative and qualitative composition of the microbiota in stool and meconium samples.
  
  

  • ENTEROFLOR® Kiddy
• PCR diagnostics of nosocomial and community-acquired infections

  Opportunistic pathogenic microorganisms (UPM) cause infectious diseases similar in clinical manifestation, therefore it is impossible to accurately identify the pathogen without laboratory tests. Differential diagnosis is necessary for the selection of therapy, including in connection with the acquisition of new properties of UPM, such as antibiotic resistance and the ability to adhere and film formation.
  
  

  • BacScreen OM
• Respiratory tract infections

  PCR is the diagnosis of pathogens of acute respiratory diseases. Comprehensive studies are presented to identify a wide group of potential pathogens, as well as single tests for a specific type of virus or bacterium.
  
  

  • AVRI Panel Multiplex
  • AVRI Screen
  • Influenza A Virus
  • Influenza B Virus
  • Influenza A Virus H1N1pdm09
  • Influenza A virus H1N1pdm09/H3N2 Multiplex
  • SARS-CoV-2/RSV/ Influenza AB virus Multiplex
  • C. diphtheriae Tox

Ask questions

Please note that the specialists of the DNA Technology company provide consultations exclusively to medical specialists on the application and research features. Requests related to the appointment, delivery, or interpretation of tests are not considered. For relevant information, we recommend contacting the laboratory directly.

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