Molecular diagnostics in general internists’ practice.
PCR methods as a tool for internists: diagnosing infections and genetic testing.
Diagnosis and treatment of respiratory infections are central to the internists’ work: more than 90% of all visits to outpatient care are related to colds. PCR testing for acute respiratory viral infections, including influenza A and B viruses and the SARS-CoV-2 coronavirus, is becoming a key diagnostic tool for a modern-day physician.
Certainly, internists’ job is not limited to treating respiratory diseases; PCR diagnostics is also effectively used to detect pathogens causing hepatitis, tuberculosis, HIV and bacterial infections, including nosocomial ones. The PCR method allows for the rapid and accurate detection of pathogens at an early stage of infection, bypassing the serological window.
In addition, modern methods of molecular diagnostics expand the possibilities of internists in the field of genetics. Such studies make it possible to identify the genetic characteristics of a patient's metabolism, which may be relevant for selecting an individualized therapeutic approach and choosing the most effective treatment methods.
Our research
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Fungal infectionsA real-time PCR study makes it possible to identify the causative agent of infection with type-level precision in the shortest possible time and select an antimycotic drug correctly.
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Identification of antibiotic resistance genesThe BacResista GLA study is designed to identify genes of resistance to glycopeptide and beta-lactam antibiotics in DNA preparations.
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Nosocomial infectionsOpportunistic pathogens (OP) cause infectious diseases similar in clinical manifestation; therefore, it is impossible to accurately identify the pathogen without laboratory tests. Differential diagnosis is necessary for the selection of therapy, including in connection with the acquisition of new properties of OP, such as antibiotic resistance and the ability to adhere and form films.
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Respiratory tract infectionsThe PCR method is used to diagnose pathogens of acute respiratory diseases. Comprehensive studies are available to identify a wide group of potential pathogens, as well as single tests for a specific type of virus or bacterium.
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