ENTEROFLOR® Kiddy

We recommend ENTEROFLOR^®_Kiddyin the following cases:

• Intestinal dysfunction in children during intensive antibiotic and/or immunosuppressive therapy, prolonged chemotherapy, or hormonal therapy
• Prolonged recovery period after dysentery and other acute intestinal infectious diseases
• Preoperative period in individuals with risk factors for developing intestinal dysbiosis
• Intrauterine infection
• Allergic diseases (atopic dermatitis, bronchial asthma, etc.) that are difficult to treat
• Early artificial feeding
• Breast milk intolerance
• Immunodeficiency conditions
• Frequent acute respiratory infections
• Stomatitis, oral thrush
• Monitoring the formation of intestinal microbiota in infants during the first year of life
• Delayed weight gain or weight loss, delayed physical development

Specific report is formed automatically:

• Page 1 of the report contains brief description of gut microbiota state and a final table with the main assay results.
• Page 2 of the report contains a table with full list of assay results.
Бланк исследования ЭНТЕРОФЛОР® Дети (2 стр).pdf Download

ENTEROFLOR® Kiddy: Questions

• Why are there so many microorganisms in the test?

  Human gut microbiota is a complex, dynamic system composed of multiple microorganism groups interacting with each other and human organism and performing a number of important duties. To assess gut microbiota properly, we need to view all the microorganism groups as parts of the whole. ENTEROFLOR® Kiddy includes 43 indicators comprising at least 99.9% of children’s gut microbiota.
• Why is there no opportunity to diagnose acute enteric infections (AEI) in ENTEROFLOR® Kiddy? What are the actions, if the patient has AEI symptoms?

  ENTEROFLOR® Kiddy is designed to diagnose gut dysbiosis associated with chronic inflammations, prolonged digestion disruption, antibiotics intake, etc. If a patient has AEI symptoms (vomiting, diarrhea, stomach pains), in the cases where no AEI agents are detected, ENTEROFLOR® Kiddy can be assigned.
• Can biomaterial of patients older than 14 years of age be tested by ENTERFLOR® Kiddy?

  Specific report forming algorithm is developed for children under 14. For biomaterial of the older patients, final gut microbiota assessment may be difficult.
• Can ENTEROFLOR® Kiddy results be compared to microbiological dysbiosis analysis? Will the results match?

  Dysbiosis analysis and PCR are based on two different technologies, thus the results may differ. Feces culture for dysbiosis involves detection of certain bacteria and fungi, unlike standard culture where a wide range of microorganisms is cultivated on various nutrient media. However, dysbiosis analysis has limitations typical for microbiological analysis as a whole: 50–80% of microorganisms composing gut microbiota are hard to cultivate and, therefore, not detected by this method. Culture results depend directly on microorganisms’ viability and, consequently, the time interval between biomaterial collection and its delivery to the lab, sample transport and storage conditions. ENTEROFLOR® Kiddy utilizes a direct microorganisms’ diagnostic method by DNA fragments which does not require the bacterial viability.
• Why are normal values for ENTEROFLOR® Kiddy do not match the values for microbiological dysbiosis analysis?

  Traditional dysbiosis analysis, based on stool culture with its inherent limitations, used reference norms for just two broad age groups (under and over 1 year). In contrast, real-time PCR technology enables a broader detection panel and has facilitated the establishment of precise, age-specific reference ranges. The fundamental differences between these technologies are explained in detail above.